Sunday, 23 December 2018

World-First Pill May Stop Parkinson’s


Most medications and therapies available today to treat Parkinson’s disease – an ailment affecting approximately 10 million people worldwide – do more to reduce or relieve symptoms than to prevent the actual illness progression. There is a new therapy, however, that is specifically designed to stop Parkinson’s “in its tracks” and will begin its first phase of clinical trials on humans during the coming year! Here’s what you should know!

World-First Pill Designed To Stop Parkinson’s Disease!

Parkinson’s disease is the second most common neurodegenerative disease currently known. This therapy to treat Parkinson’s has been developed by University of Queensland researchers, partially underwritten by the Michael J. Fox Foundation, and it is considered world first due to its supposed ability to stop the death of brain cells in individuals suffering from Parkinson’s, rather than simply managing their troubling symptoms and ailments.
According to Trent Woodruff, Associate Professor in the Faculty of Medicine at the University of Queensland, the research group was quickly successful at discovering “a key underlying driver for the disease” that served as a therapy breakthrough. This key, small molecule, MCC950, is a compound that was previously developed, but then also abandoned over a decade ago by a massive pharmaceutical company that didn’t fully understand how the compound worked. Parkinson’s was misunderstood when the compound was first discovered, leading to many research mistakes. The University of Queensland’s research discovery, however, helped researchers identify possible solutions to the mysterious disease.
According to the researchers, if the human trials to come echo the stunning results found in any of the animal tests, then the inflammation of the brain that most commonly causes the greatest amount of progressive damage in cases of Parkinson’s disease could be completely calmed. This could be possible if a patient simply takes a single pill every day. (1, 2)

How Does This Pill Work Against Parkinson’s?

According to Dr. Woodruff, Parkinson’s disease is specifically characterized by the loss of the brain cells that normally work to produce dopamine, a chemical aiding your body by coordinating motor control. Therefore, the loss of dopamine has been a clear focus of the entire treatment, as has the issue of chronic inflammation that occurs when an individual’s immune system response malfunctions, resulting in a great deal of inflammation and brain damage. But during their investigations, Woodruff and his team of researchers discovered five years ago that the immune system causes the NLRP3 inflammasome to light up in patients suffering from Parkinson’s. Not only that, but signals can be found in the brain and even the blood!

It was after this miraculous discovery that Woodruff and his team realized that when the tiny molecule MCC950 is given orally, once per day, it “blocked NLRP3 activation in the brain and prevented the loss of brain cells, resulting in markedly improved motor function.” The progression of MCC950 has since escalated fairly quickly, leading many to believe its journey to the market will happen just as fast. Both Michael J. Fox Foundation for Parkinson’s Research and Inflazome, an Ireland-based company, is eager for the human trials of this compound to begin as soon as possible, and they have been scheduled for the new year. 
According to Woodruff, the hardest part of this research has already been completed, apart from funding, and that is that MCC950 came off a patent. Since much of the preclinical work has already been completed, this means researchers have been allowed to develop variations of the drug for many different intellectual property reasons. These newest versions of the drug are under testing currently and proving to be even more effective, per Dr. Woodruff.

Conclusion

Parkinson’s disease is a serious neurodegenerative disease that has been under investigation and research for years. The phase-one testings of this saving pill scheduled for next year will help determine if the drug is safe to use on healthy people. After this, if all goes well, volunteers with Parkinson’s will be recruited for phase-two testing in the year 2020. Woodruff and his researchers are optimistic, but only time and testing will truly tell the safety and effectiveness of this drug.

What Happens To Your Body When You Smoke Cannabis For a Month?


For starters, this is not a scientific test and only gives you a visual as to what is going in your body. We’ve posted in the past about the effects of vaping on your lungs. Now it’s time to show you lovely people the effect of smoking cannabis.
Nothing was mixed with the cannabis such as tobacco. “RAW” rolling paper was used and each cigarette had approximately .5 to .6 grams of cannabis.
The amount of smoke shown in the video comes out of 90 joints. With the idea of smoking 3 joints a day. That’s the average amount of joints a cannabis smoker smokes each day.
We are absolutely no pro advocates of smoking. We are just here to inform. That’s why this has to be said; “If anyone tries to get you to vape, smoke or try a joint, just say no thank you and walk away. There is only one thing that was meant to go in your lungs and that’s air.
In the following video you’ll find the results:

Source: youtube

A Color Test That Can Tell Your Mental Age: How Old Is Your Brain?


How old are you? We know – it’s not always polite to ask someone they age. But did you know there is actually more than one way to answer that question? In fact, there are three types of age. Chronological age refers to the number of years you’ve been alive (i.e., the answer almost every gives). Biological age refers to how old your body feels. Lastly, mental age refers to how old your brain feels.
Some of you are believers that age is merely a number for the very reasons we just mentioned. You could be younger yet feel older and vice versa. But of all three types of ages, one of them is harder to pinpoint: mental age. So, we’ve put together a quick visual test to help you figure out how old your brain really is.

Do You Really Know Your Mental Age?

All you have to do is choose an answer and add up all the “years” to learn the age of your brain. Let’s get started!

1) Where are your eyes drawn first?

  • Black (1)
  • Reddish-Organge (3)
  • Peach (5)
  • Light Blue (6)
  • Navy blue (7)

2) Which color is the brightest?


  • Amber (10)
  • Pink (3)
  • Purple (6)
  • Yellow (2)
  • Blue (8)

3) What direction is the woman looking?

  • To her right (3)
  • Right at you (8)

4) Is this photo black and white?

  • Yes (0)
  • No (5)

5) Are these two photos the same?

  • Yes (10)
  • No (5)

6) Choose a shade

  • One (3)
  • Two (4)
  • Three (6)
  • Four (8)
  • Five (10)

So, How Old Are You Really?

Go ahead and add up all the “years” you got and check your mental age out below!
If you got 15 or less, your mental age is 20-years-old and under. At heart, you’re a care-free teenager regardless of the year you were born.
If you got 16 to 24, your mental age is 21 to 29-years-old. Technically, you’re an adult but you are still feeling active, creative, and full of life!
If you got 25 to 34, your mental age is 30- to 40-years old. You’ve lived a little and know the true meaning of responsibility. But you still love learning new things!
If you got 35 to 44, your mental age is 41 to 50-years-old. You’re more mature than you know and don’t get caught up in the trivial riff raff that troubles the average person.
If you got 45 to 50, you mental age is 50-years-old and over. You’re ageing gracefully and love to share wisdom with the people around you. You know how to appreciate the simple things and life’s little comforts.

Sunday, 19 August 2018

10 things that the rich bought


One of the most famous people who convert ordinary products into precious possessions for the rich is famous for turning it into things such as televisions, mobile phones, PlayStation and Xbox devices into very precious items by decorating them with gold, diamonds and precious jewels and after furnishing them to sell them at fabulous prices. The world's 55-inch television is adorned with 28 kilograms of 18-pound pink gold, and the TV frame is adorned with seventy-two pieces of diamonds. Already a large number of the wealthy bought this television, Million dollars.




One of the royal family in Abu Dhabi and considered one of the richest people in the world, attracted the attention of the world when he decided to buy his own island and not only that, but decided to dig his name with a giant size and was engraved each letter of his name up to a kilometer and the goal is that can He or anyone can see his name from space clearly on the ground and the letters that are dug form waterways that absorb the tidal creep to prevent the name from being cleared from the island.
Russian businessman Roman Abramovich is known for his $ 11.2 billion fortune. He has decided to buy a $ 450 million yacht, the world's largest and most private yacht. The yacht is about 170 meters long and has a missile defense system and underwater sensors, Two helipads, a private swimming pool, a gym, a 15-meter long dash, a 12-seater submarine from the bottom of the yacht, a 50-meter underwater dive and a yacht worth $ 1.2 billion as the world's largest yacht.


An Indian man ranks fourth in the list of the world's wealthiest people. His fortune is estimated at 29 billion dollars. He decided to pay a large part of his money to build a private house, but not a house. The house is a giant skyscraper of 27 floors for his personal use, his family and a total area of more than one million two hundred The house is about 170 meters above the Mumbai neighborhoods and contains two helipads and a 50-seat cinema. The building has about 600 workers and is the most expensive private residence in the world after Buckingham Palace.

An Australian company for toilet paper launched in 2013 a new type of paper made of 22-caliber gold and offered a roll of one paper at a price of one million and 376 thousand dollars and confirmed that it is easy to use and provides comfort and softness such as ordinary napkins completely and already bought by a large number of people both for personal use or to provide gifts as a kind of Luxury gifts....
Known for his desire to collect special cars and when he liked to add piece 38 to his group bought a Mercedes Benz car studded with diamonds and jewelry and not only part of the car is inlaid with diamonds, but the car, including the complete ventilation pipe and door handles and even the car logo, where $ 48 million was spent on this car and said that Allows the public to approach, touch or visualize it for $ 1,000.
Henry Graves was sold with an auction in Switzerland for about $ 25 million. Henry Graves is a US banker who has asked for the most sophisticated clocks in history for the famous Swiss watchmaker Patek Philippe in 8 years and completed its manufacture in 1933, weighing approximately 450 g and 7 cm wide. It is made of pure gold and performs many tasks in addition to knowing the time such as the result and the timing of sunrise and sunset and monitoring the movement of stars in the sky and considered by the watch experts as one of the most important clocks and clocks made in history and was sold to Sheikh Saud bin Mohammed Al Thani of the ruling family in Qatar in 1999 At $ 1 1 million dollars and the price at the auction in Switzerland in 2014 to 25 million, but did not announce the identity of the new buyer.

One of Leonardo Da Vinci's greatest admirers, but his admiration is more closely related to his inventions and scientific discoveries than his artistic drawings. He has thus made a fictional number in a collection of the scientific writings of Da Vinci, known as the Luster manuscript, which was announced at the auction in 1994 and then allowed to be exhibited to the public. View it in a different city.
One of Leonardo Da Vinci's greatest admirers, but his admiration is more closely related to his inventions and scientific discoveries than his artistic drawings. He has thus made a fictional number in a collection of the scientific writings of Da Vinci, known as the Luster manuscript, which was announced at the auction in 1994 and then allowed to be exhibited to the public. View it in a different city.

Is the Sultan of the Kingdom of Brunei and estimated his fortune by about 20 billion dollars and some sources claim that 40 billion, the Sultan at one time to pay 15 thousand dollars for a London barber to shave his hair next to the provision of a special proof and locked barber so as not to get any kind of diseases even No infection is transmitted to the Sultan as he cuts his hair.

In addition, his car is fully gold-plated and is known as the star of India and the price of this car is 14 million dollars and of course when he thinks of a special plane must be a distinctive plane has bought a Boeing 747, one of the largest aircraft in the world $ 100 million and spent 120 Million dollars to make some additions to the plane, such as changing the interior decoration in full so that everything is plated with pure gold including bath tub and toilet.





Tuesday, 31 July 2018

9 Easy Ways To Look Sexy and Seduce The Man You Like, Girls Good To Know This!!


Is there a single woman in the world that does not want to look attractive? We think there isn’t. That is why we decided to come up with a few tricks to make you look even sexier and more attractive than ever. It goes without saying, that each woman has her own, unique beauty. There are no ‘ugly’ or ‘unbeautiful’ women in this world.

But, unlucky, not all of them are able to present all their advantages in good lights. That’ s exactly why we are here today! Today, we’ll teach you how to reveal your beauty with a help of some interesting and – sometimes – surprising hacks! Follow our advice and observe the change. And the results will not keep itself waiting!

#1. Buy a red dress The color of your outfit matters. It is official – women who are wearing red are more attractive. Still do not have a nice red dress? What are you waiting for?


#2. Make an eye contact If you are interested in someone do not be afraid to show it. Make eye contact, there is nothing wrong with it.

#3. Be different

Looking like everyone else will do you no good. People are attracted to those who are different and are not afraid of expressing themselves. You may have a heart of gold but no one will notice it at first glance.

#4. Light touches are good Body language matters. Do not be afraid to show the person that you are interested by a slight touch on the arm.

#5. Stand up When there are a lot of people do not be afraid of standing out by standing up. If attention is what you are seeking.

#6. Watch the light The lighting also matters. Dimmed lights create a more intimate environment.

#7. Choose your personal smell The way you smell matters. But that does not mean that people should feel that they are suffocating and fight the urge to step away from you due to your fragrance being too intense. Spray yourself just enough for people to be willing to catch your scent and to get closer to you. READ MORE: Fitness trainer gives 10 best exercises for women weight loss

#8. Wear suitable jewelry Do not leave out your wrists. Let them take part in the game too. We are not saying that you should put every piece of jewelry you possess on, but a subtle highlight will totally do.

#9. Imagine that you’re a queen

The way you stand can also either attract people to you or make them not even notice that you were there. Stand in such a way as if you are on a stage and dozens of cameras are pointed at you, do not hunch your back or anything. Show them the inner pride!

Tuesday, 12 June 2018

She mixed only 2 ingredients and got miraculous preparation to solve the big problem with the skin!



See how to revitalize your face and solve the greatest torments with which all meet. With this mask blackheads will become history.

Ingredients:

- Gelatin

- Milk

Preparation:

Put 1 tablespoon of gelatin in a bowl, then add 2 tablespoons of milk and stir.
Wash your face and mixture put in the microwave for 15 seconds.

Put the warm mixture on your face immediately in order to ensure the desired smoothness.

Leave the mixture on your face for 15 minutes.

When dried, slowly peel the mask from your face. Wash your face with warm water. The results are noticeable after the first treatment.

Friday, 30 March 2018

10 Home Remedies For Candida


Many common ailments are caused by the Candida albicans fungus. Diaper rash, thrush, a skin infection or a yeast infection in women — all are due to an overgrowth of the yeast fungus.
Though not a serious condition, it’s important to treat a Candida infection as soon as you notice symptoms. In addition to minimizing discomfort, early treatment will reduce the risk of the infection spreading and your susceptibility to more serious conditions.
Candida is normally present on your skin and in your mouth and gastrointestinal tract without causing any harm. In women, it is also present in the vagina.
However, an overgrowth of Candida can cause candidiasis, giving rise to symptoms like intense itching and redness. It can affect the skin, mouth, stomach, urinary tract and vagina.
  • When it affects the mouth, it is called an oral thrush and is characterized by a creamy, white coating or patches in the mouth.
  • On the skin, it leads to rashes and blisters, especially on skin folds.
  • Vaginal yeast infections cause itching and a white, cottage cheese-like discharge.
A variety of factors can increase your risk of developing a Candida infection, such as a weakened immune system, a bacterial infectionprolonged use of antibioticsbirth control pills, and pregnancy.
People who have diabetes also tend to be more prone to this problem. Moreover, the Candida fungi thrive in warm, moist areas.
Chronic Candida infections can cause issues like fatigue, lightheadedness, irritability, and poor memory. Whether you are dealing with a single instance of the infection or chronic reoccurrence, several simple home remedies can help you treat it and relieve symptoms.
Here are the top 10 home remedies for Candida.

1. Garlic

Garlic has a number of sulfur-containing compounds that give it natural antifungal properties that help fight Candida infections.
  • It’s a good idea to include garlic in your regular diet due to its many health benefits. You can have two to four raw garlic cloves a day. Crushing the cloves first helps release their beneficial properties.
  • If you do not like the taste of garlic, you can take garlic supplements. The dosage usually depends on the severity of the condition, but the general recommendation is 600 to 900 mg daily.
  • You can also apply raw, crushed garlic cloves on the affected area.

2. Coconut Oil

Coconut oil works as an effective remedy for candidiasis due to its medium-chain fatty acids like lauric, caprylic and capric acid.
Studies show that these saturated fats have antimicrobial properties that help kill Candida fungi without leading to the development of strains of Candida that are more resistant to other antifungal treatments.
  • Apply coconut oil topically on the affected area three or four times a day until you see improvement.
  • You can also include it in your daily diet. Start with one teaspoon of organic virgin coconut oil daily, gradually increasing the dosage to up to three tablespoons per day.

3. Yogurt

The probiotics present in yogurt, especially yogurt with live cultures, are helpful in fighting off candidiasis or yeast infection. The Lactobacillus acidophilus culture, in particular, keeps Candida yeast in check by producing lactic acid.
  • Make plain yogurt with live lactobacillus acidophilus part of your daily diet.
  • To treat a vaginal yeast infection, you can apply it by inserting a tampon dipped in yogurt. Do this two times a day until the infection clears.

4. Tea Tree Oil

Tea tree oil is another effective natural cure for candidiasis as it has antifungal and antibacterial properties.
  • For vaginal yeast infection, put several drops of tea tree oil on a tampon and insert it. Replace it every four to six hours.
  • For oral thrush, add five to seven drops of pure tea tree oil to a cup of water and gargle with it for a few minutes twice daily until the infection clears. Do not swallow the solution.

5. Oil of Oregano

Oregano oil contains a compound called carvacrol that has been found to inhibit growth of Candida yeast. Scientific studies also found that the oil’s antifungal and antimicrobial agents can be effective in treating as well as preventing candidiasis.
  • Mix three drops of oregano oil with one tablespoon of olive oil. Apply it on the affected area and leave it on for a few hours. Do this daily until you see improvement.
  • Alternatively, mix three drops of oregano oil in a glass of water. Drink it twice daily for a few days to a week.
  • If you are taking oregano oil capsules, take one or two capsules twice a day after meals. Continue the treatment for two to three months.
When purchasing oil of oregano, look for a product that does not contain alcohol and has a high level of carvacrol.

6. Apple Cider Vinegar

Apple cider vinegar is also considered beneficial for treating Candida infections as it helps restore your body’s natural pH balance.
It is also rich in enzymes that help regulate the presence of Candida. It creates an unfavorable environment for the fungi and encourages healthy gut bacteria to balance the flora in your intestinal tract.
  • Add one tablespoon of organic raw apple cider vinegar to a glass of water. Sip it slowly before a meal. Do this daily until symptoms subside. Symptoms may worsen during the first few days due to the yeast dying off, but you will notice improvement after that.
  • You can also apply apple cider vinegar on the affected area or mix one cup of it in warm bath water and soak in the bath for about 15 minutes. Do this daily for a few days.

7. Olive Leaf

olives leaves
Olive leaf is a potent destroyer of Candida yeasts and fungi due to its natural antifungal properties. Plus, it has active ingredients called oleuropein that stimulate the immune system.
  • Make olive leaf tea by steeping one or two teaspoons of the herb in a cup of boiling water for about 15 minutes. Drink two to three cups a day.
  • You can also take olive leaf extract (250 to 500 mg) three times a day.
When the infection clears, continue to drink a cup or two of olive leaf tea or herbal infusion daily as a preventive measure.

8. Cranberries

cranberry
Cranberries contain a compound called arbutin that helps kill Candida albicans.
  • Drink a glass of unsweetened cranberry juice two or three times a day for a few weeks to clear out Candida yeast.
  • You can also take cranberry tablets two or three times a day.

9. Cinnamon

cinnamon
Cinnamon has been found to be active against Candida albicans due to its antibacterial, antifungal and antiparasitic properties. Studies also found anticandidal activity when using cinnamon oil against other types of Candida yeast, too.
So, include cinnamon in your regular diet by adding it to your yogurt, sprinkling it on your French toast, or simply having cinnamon tea.
The typical dosage of ground cinnamon bark is one to four grams a day (1 gram of cinnamon is approximately a quarter or one-half teaspoon); the typical dose of cinnamon oil is 0.05 to 0.2 grams daily. Follow this treatment for one or two months.

10. Black Walnut

black walnut
Black walnut bark contains high levels of tannins that have powerful antifungal and astringent properties. It also has an active ingredient, juglone, which has been found to have moderate antifungal and antibiotic effects. To treat a Candida infection, you can take black walnut extract or capsules according to the directions on the label.
In addition to these remedies, you can help prevent growth or spread of Candida by restricting your intake of foods high in carbohydrates and sugars, which tend to fuel yeast growth in the intestine. Plus, you can take probiotics and probiotic supplements. If the infection does not clear within a few weeks, consult your doctor.